54221 is zip code located in Manitowoc, Wisconsin. The population is , making 54221 the 2nd largest zipcode in Manitowoc.
There are 0 public schools in 54221 with an average Homefacts rating of NA. The total crime rate for Manitowoc is very low , and there are 0 registered sex offenders residing in the zip code 54221. Unemployment in 54221 is moderate.
Zip codes within Manitowoc include 54220.