22649 is zip code located in Middletown, Virginia. The population is , making 22649 the 2nd largest zipcode in Middletown and the 8th largest in Frederick County.
There are 0 public schools in 22649 with an average Homefacts rating of NA. The total crime rate for Middletown is very low , and there are 0 registered sex offenders residing in the zip code 22649. Unemployment in 22649 is low.
Zip codes within Middletown include 22645.